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Reverse Polarization in Amino acid and Nucleotide Substitution Patterns Between Human–Mouse Orthologs of Two Compositional Extrema

Genome-wide analysis of sequence divergence patterns in 12 024 human–mouse orthologous pairs reveals, for the first time, that the trends in nucleotide and amino acid substitutions in orthologs of high and low GC composition are highly asymmetric and polarized to opposite directions. The entire data...

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Detalhes bibliográficos
Main Authors: Bag, Sumit K., Paul, Sandip, Ghosh, Subhagata, Dutta, Chitra
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533592/
https://ncbi.nlm.nih.gov/pubmed/17895298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/dnares/dsm015
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