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Multi-Component One-pot Synthesis of the Tumor-Associated Carbohydrate Antigen Globo-H Based on Pre-activation of Thioglycosyl Donors

Two efficient routes for rapid assembly of the tumor-associated carbohydrate antigen Globo-H hexasaccharide 2 by the pre-activation based iterative one pot strategy are reported. The first method involves the sequential coupling of four glycosyl building blocks, leading to the desired hexasaccharide...

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Autores principales: Wang, Zhen, Zhou, Luyuan, El-Boubbou, Kheireddine, Ye, Xin-shan, Huang, Xuefei
Formato: Artigo
Lenguaje:Inglês
Publicado: 2007
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533580/
https://ncbi.nlm.nih.gov/pubmed/17658849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo070585g
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