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Rolling Circle Amplification, a Powerful Tool for Genetic and Functional Studies of Complete Hepatitis B Virus Genomes from Low-Level Infections and for Directly Probing Covalently Closed Circular DNA

Complete characterization of the biological properties of hepatitis B virus (HBV) variants requires the generation of full-length genomes. The aim of this study was to develop new tools for the efficient full-length genome amplification of virus from samples with low viral loads. Rolling circle ampl...

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Hlavní autoři: Margeridon, Séverine, Carrouée-Durantel, Sandra, Chemin, Isabelle, Barraud, Luc, Zoulim, Fabien, Trépo, Christian, Kay, Alan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533481/
https://ncbi.nlm.nih.gov/pubmed/18606836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01318-07
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