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Anti-Human Immunodeficiency Virus Type 1 Activities of Antimicrobial Peptides Derived from Human and Bovine Cathelicidins

From among 15 human cathelicidin LL-37-derived peptides, FK-13 was identified as the smallest peptide active against human immunodeficiency virus (HIV) and GI-20 had the highest therapeutic index, which was twice that of LL-37. BMAP-18, which is derived from bovine cathelicidin BMAP-27, possessed a...

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Detalhes bibliográficos
Main Authors: Wang, Guangshun, Watson, Karen M., Buckheit, Robert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533476/
https://ncbi.nlm.nih.gov/pubmed/18591279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00452-08
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