Inhibitors of Bacterial Multidrug Efflux Pumps Potentiate Antimicrobial Photoinactivation

Antimicrobial photodynamic inactivation (APDI) combines a nontoxic photoactivatable dye or photosensitizer (PS) with harmless visible light to generate singlet oxygen and reactive oxygen species that kill microbial cells. Cationic phenothiazinium dyes, such as toluidine blue O (TBO), are the only PS...

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Detalhes bibliográficos
Main Authors: Tegos, George P., Masago, Kayo, Aziz, Fatima, Higginbotham, Andrew, Stermitz, Frank R., Hamblin, Michael R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Mechanisms of Action: Physiological Effects
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533468/
https://ncbi.nlm.nih.gov/pubmed/18474586
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00006-08
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