Efficacy of Quinoxaline-2-Carboxylate 1,4-Di-N-Oxide Derivatives in Experimental Tuberculosis

This study extends earlier reports regarding the in vitro efficacies of the 1,4-di-N-oxide quinoxaline derivatives against Mycobacterium tuberculosis and has led to the discovery of a derivative with in vivo efficacy in the mouse model of tuberculosis. Quinoxaline-2-carboxylate 1,4-di-N-oxide deriva...

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Detalhes bibliográficos
Main Authors: Vicente, Esther, Villar, Raquel, Burguete, Asunción, Solano, Beatriz, Pérez-Silanes, Silvia, Aldana, Ignacio, Maddry, Joseph A., Lenaerts, Anne J., Franzblau, Scott G., Cho, Sang-hyun, Monge, Antonio, Goldman, Robert C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533452/
https://ncbi.nlm.nih.gov/pubmed/18625764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00379-08
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