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C(2)-symmetric bisamidines: Chiral Brønsted bases catalysing the Diels-Alder reaction of anthrones

C(2)-symmetric bisamidines 8 have been tested as chiral Brønsted bases in the Diels-Alder reaction of anthrones and N-substituted maleimides. High yields of cycloadducts and significant asymmetric inductions up to 76% ee are accessible. The proposed mechanism involves proton transfer between anthron...

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Detalhes bibliográficos
Main Authors: Akalay, Deniz, Dürner, Gerd, Bats, Jan W, Göbel, Michael W
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533436/
https://ncbi.nlm.nih.gov/pubmed/18941500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.4.28
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