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Genomic analysis of the TRIM family reveals two groups of genes with distinct evolutionary properties
BACKGROUND: The TRIM family is composed of multi-domain proteins that display the Tripartite Motif (RING, B-box and Coiled-coil) that can be associated with a C-terminal domain. TRIM genes are involved in ubiquitylation and are implicated in a variety of human pathologies, from Mendelian inherited d...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533329/ https://ncbi.nlm.nih.gov/pubmed/18673550 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-8-225 |
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