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The Pseudomonas aeruginosa multidrug efflux regulator MexR uses an oxidation-sensing mechanism
MexR is a MarR family protein that negatively regulates multidrug efflux systems in the human pathogen Pseudomonas aeruginosa. The mechanism of MexR-regulated antibiotic resistance has never been elucidated in the past. We present here that two Cys residues in MexR are redox-active. They form interm...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2008
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533233/ https://ncbi.nlm.nih.gov/pubmed/18757728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803391105 |
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