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The Hsp70 chaperone system maintains high concentrations of active proteins and suppresses ATP consumption during heat shock

Hsp70 chaperones assist protein folding by cycling between the ATP-bound T state with low affinity for substrates and the ADP-bound R state with high affinity for substrates. The transition from the T to R state is catalyzed by the synergistic action of the substrate and DnaJ cochaperones. The rever...

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Bibliografski detalji
Glavni autori: Hu, Bin, Tomita, Masaru
Format: Artigo
Jezik:Inglês
Izdano: Kluwer Academic Publishers 2007
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533148/
https://ncbi.nlm.nih.gov/pubmed/19003436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11693-006-9004-2
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