Reduction of experimental diabetic vascular leakage by delivery of angiostatin with a recombinant adeno-associated virus vector

PURPOSE: To evaluate the efficacy of recombinant adeno-associated virus (rAAV) vector expressing mouse angiostatin (Kringle domains 1 to 4) in reducing retinal vascular leakage in an experimental diabetic rat model. METHODS: rAAV-angiostatin was delivered by intravitreal injection to the right eyes...

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Hlavní autoři: Shyong, Mong-Ping, Lee, Fenq-Lih, Kuo, Ping-Chang, Wu, Ai-Ching, Cheng, Huey-Chung, Chen, Show-Li, Tung, Tao-Hsin, Tsao, Yeou-Ping
Médium: Artigo
Jazyk:Inglês
Vydáno: Molecular Vision 2007
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533034/
https://ncbi.nlm.nih.gov/pubmed/17293777
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