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Differential expression of the TFIIIB subunits Brf1 and Brf2 in cancer cells

BACKGROUND: RNA polymerase (pol) III transcription is specifically elevated in a variety of cancers and is a target of regulation by a variety of tumor suppressors and oncogenes. Accurate initiation by RNA pol III is dependent on TFIIIB. In higher eukaryotes, two forms of TFIIIB have been characteri...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cabarcas, Stephanie, Jacob, Joby, Veras, Ingrid, Schramm, Laura
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533013/
https://ncbi.nlm.nih.gov/pubmed/18700021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2199-9-74
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