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Synthetic Seleno-Glutaredoxin 3 Analogs are Highly Reducing Oxidoreductases with Enhanced Catalytic Efficiency

Selenoenzymes have a central role in maintaining cellular redox potential. These enzymes have selenenylsulfide bonds in their active sites that catalyze the reduction of peroxides, sulfoxides and disulfides. The selenol/disufide exchange reaction is common to all of these enzymes and the active site...

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Bibliografiske detaljer
Main Authors: Metanis, Norman, Keinan, Ehud, Davison, Philip E.
Format: Artigo
Sprog:Inglês
Udgivet: 2006
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532977/
https://ncbi.nlm.nih.gov/pubmed/17177418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0661414
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