The RNA-binding protein XSeb4R: a positive regulator of VegT mRNA stability and translation that is required for germ layer formation in Xenopus

VegT represents a localized maternal determinant essentially required for endoderm formation in Xenopus. Here, we report on the identification of the RNA-binding protein XSeb4R as a positive regulator of VegT. XSeb4R interacts directly with the 3′-untranslated region of VegT mRNA, stabilizes it, and...

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Autores principales: Souopgui, Jacob, Rust,, Barbara, Vanhomwegen, Jessica, Heasman, Janet, Henningfeld, Kristine A., Bellefroid, Eric, Pieler, Tomas
Formato: Artigo
Lenguaje:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2008
Materias:
Research Communication
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532925/
https://ncbi.nlm.nih.gov/pubmed/18765788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.479808
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