Large T antigens of simian virus 40 and polyomavirus efficiently establish primary fibroblasts.

Recombinant retroviruses that transduce the simian virus 40 (SV40) large T antigen or the polyomavirus large T antigen as well as encoding resistance to antibiotic G418 were used to investigate whether these genes alone were sufficient for immortalization of primary cells. The results provided defin...

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Bibliographic Details
Published in:J Virol
Main Authors: Jat, P S, Sharp, P A
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1986
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253254/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3016337/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.59.3.746-750.1986
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