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Expression of reverse transcriptase activity of human T-lymphotropic virus type III (HTLV-III/LAV) in Escherichia coli.

The pol gene from a biologically active clone of the human T-cell lymphotropic virus type III provirus was inserted into a bacterial expression vector. The resulting gene fusion induced the formation of active reverse transcriptase that could be readily detected in extracts of bacterial cells. The a...

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Udgivet i:J Virol
Principais autores: Tanese, N, Sodroski, J, Haseltine, W A, Goff, S P
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1986
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253253/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2426471/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.59.3.743-745.1986
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