Wnt3a-mediated formation of phosphatidylinositol 4,5-bisphosphate regulates LRP6 phosphorylation

The canonical Wnt-β-catenin signaling pathway is initiated by induction of phosphorylation of one of the Wnt receptors, low density lipoprotein receptor-related protein (LRP) 5/6, at Thr(1479) and Ser(1490). We identified, by screening a human kinase siRNA library, phosphatidylinositol 4-kinase type...

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Detaylı Bibliyografya
Asıl Yazarlar: Pan, Weijun, Choi, Sun-Cheol, Wang, He, Qin, Yuanbo, Volpicelli-Daley, Laura, Swan, Laura, Lucast, Louise, Khoo, Cynthia, Zhang, Xiaowu, Li, Lin, Abrams, Charles S., Sokol, Sergei Y., Wu, Dianqing
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2008
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532521/
https://ncbi.nlm.nih.gov/pubmed/18772438
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1160741
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