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Double Barrel Shotgun Scanning of the Caveolin-1 Scaffolding Domain
In the post-genomic era, a major challenge remains elucidating the thermodynamic forces governing receptor-ligand specificity and promiscuity. We report a straightforward approach for mapping sidechain contributions to binding for the multi-partner interactions characteristic of the human proteome....
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2532506/ https://ncbi.nlm.nih.gov/pubmed/17602618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb700055t |
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