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Proviral-activated c-erbB is leukemogenic but not sarcomagenic: characterization of a replication-competent retrovirus containing the activated c-erbB.

Avian leukosis virus (ALV) induces erythroblastosis in chickens by integrating its DNA into the host c-erbB locus and by activating expression of truncated c-erbB transcripts. Although there is a 100% correlation of c-erbB activation with ALV-induced erythroblastosis, direct evidence that the activa...

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Bibliografiske detaljer
Udgivet i:J Virol
Principais autores: Pelley, R J, Moscovici, C, Hughes, S, Kung, H J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1988
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253246/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2833627/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.5.1840-1844.1988
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