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Three-dimensional structure of poliovirus serotype 1 neutralizing determinants.

Antigenic mutants of poliovirus (Sabin strain, serotype 1) were isolated by the resistance of the virus to anti-Sabin neutralizing monoclonal antibodies. The amino acid replacements within the capsid protein sequence causing the altered antigenicity were identified for each of 63 isolates. The mutat...

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Autors principals: Page, G S, Mosser, A G, Hogle, J M, Filman, D J, Rueckert, R R, Chow, M
Format: Artigo
Idioma:Inglês
Publicat: 1988
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC253228/
https://ncbi.nlm.nih.gov/pubmed/2451757
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