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A herpes simplex virus mutant in which glycoprotein D sequences are replaced by beta-galactosidase sequences binds to but is unable to penetrate into cells.

Herpes simplex virus (HSV) glycoprotein gD is a major component of the virion envelope and is thought to play an important role in the initial stages of viral infection and stimulates the production of high titers of neutralizing antibodies. We assumed that gD plays an essential role in virus replic...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Ligas, M W, Johnson, D C
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1988
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253172/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2833603/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.5.1486-1494.1988
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