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Structure of the catalytic domain of Streptococcus pneumoniae sialidase NanA

Streptococcus pneumoniae genomes encode three sialidases, NanA, NanB and NanC, which are key virulence factors that remove sialic acids from various glycoconjugates. The enzymes have potential as drug targets and also as vaccine candidates. The 115 kDa NanA is the largest of the three sialidases and...

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Detalhes bibliográficos
Main Authors: Xu, Guogang, Li, Xuejun, Andrew, Peter W., Taylor, Garry L.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531273/
https://ncbi.nlm.nih.gov/pubmed/18765901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309108024044
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