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Bacterial-Dependent Up-Regulation of Intestinal Bile Acid Binding Protein and Transport is FXR-Mediated Following Ileo-Cecal Resection

BACKGROUND: Bile acid reclamation following ileo-cecal resection (ICR) may prevent colonic mucosa from chronic injury. In this study, we hypothesized that in a murine model of ICR the remnant colon would upregulate the cellular machinery necessary for BA reclamation and would do so in an FXR- and ba...

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Detalhes bibliográficos
Main Authors: Dekaney, Christopher M., von Allmen, Douglas C., Garrison, Aaron P., Rigby, Rachael J., Lund, P. Kay, Henning, Susan J., Helmrath, Michael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531249/
https://ncbi.nlm.nih.gov/pubmed/18656623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.surg.2008.03.035
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