The 5′ Leader of the mRNA Encoding the Mouse Neurotrophin Receptor TrkB Contains Two Internal Ribosomal Entry Sites that Are Differentially Regulated

A single internal ribosomal entry site (IRES) in conjunction with IRES transactivating factors (ITAFs) is sufficient to recruit the translational machinery to a eukaryotic mRNA independent of the cap structure. However, we demonstrate that the mouse TrkB mRNA contains two independent IRESes. The mou...

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Autores principales: Timmerman, Stephanie L., Pfingsten, Jennifer S., Kieft, Jeffrey S., Krushel, Les A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531235/
https://ncbi.nlm.nih.gov/pubmed/18779873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003242
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