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Restriction by APOBEC3 proteins of endogenous retroviruses with an extracellular life cycle: ex vivo effects and in vivo "traces" on the murine IAPE and human HERV-K elements

BACKGROUND: APOBEC3 cytosine deaminases have been demonstrated to restrict infectivity of a series of retroviruses, with different efficiencies depending on the retrovirus. In addition, APOBEC3 proteins can severely restrict the intracellular transposition of a series of retroelements with a strictl...

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Autori principali: Esnault, Cécile, Priet, Stéphane, Ribet, David, Heidmann, Odile, Heidmann, Thierry
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531183/
https://ncbi.nlm.nih.gov/pubmed/18702815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-5-75
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