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Protein Prosthesis: 1,5-Disubstituted-[1,2,3]-triazoles as cis-Peptide Bond Surrogates

[Image: see text] Proline is unique among the natural amino acids in the similar propensity of its peptide bond to be in the cis or trans conformation. This attribute affects many processes, including the rate at which proteins fold, their structures, and their activities. Other aliphatic amino acid...

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Hlavní autoři: Tam, Annie, Arnold, Ulrich, Soellner, Matthew B., Raines, Ronald T.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2531141/
https://ncbi.nlm.nih.gov/pubmed/17914828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja075865s
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