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Mutagenesis of the avian erythroblastosis virus erbB coding region: an intact extracellular domain is not required for oncogenic transformation.

Avian erythroblastosis virus (AEV) is an oncogenic retrovirus of birds. The AEV-encoded erbB polypeptide, a transmembrane glycoprotein bearing an N-terminal domain exposed on the surface of virally transformed cells, plays a crucial role in AEV-mediated oncogenesis. We report here a characterization...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Bassiri, M, Privalsky, M L
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1986
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC253109/
https://ncbi.nlm.nih.gov/pubmed/3016316
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