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The Oxidative Stress Metabolite 4-Hydroxynonenal Promotes Alzheimer Protofibril Formation
4-Hydroxynonenal (4-HNE), formed as a consequence of oxidative stress, exists at increased concentrations in Alzheimer's disease (AD) patients and is found in amyloid β peptide (Aβ) plaques associated with AD. While it remains an open question whether oxidative stress is a causative factor or a...
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| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2007
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2530822/ https://ncbi.nlm.nih.gov/pubmed/17279615 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi061853s |
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