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The Kinetics of Mannose 6-Phosphate Receptor Trafficking in the Endocytic Pathway in HEp-2 Cells: The Receptor Enters and Rapidly Leaves Multivesicular Endosomes without Accumulating in a Prelysosomal Compartment

We have previously shown that in HEp-2 cells, multivesicular bodies (MVBs) processing internalized epidermal growth factor–epidermal growth factor receptor complexes mature and fuse directly with lysosomes in which the complexes are degraded. The MVBs do not fuse with a prelysosomal compartment enri...

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Detalhes bibliográficos
Publicado no:Mol Biol Cell
Principais autores: Hirst, Jennifer, Futter, Clare E., Hopkins, Colin R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25308/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9529379/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.9.4.809
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