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Nuclear Activities of Basic Fibroblast Growth Factor: Potentiation of Low-Serum Growth Mediated by Natural or Chimeric Nuclear Localization Signals

Human basic fibroblast growth factor (FGF-2) occurs in four isoforms: a low molecular weight (LMW FGF-2, 18 kDa) and three high molecular weight (HMW FGF-2, 22, 22.5, and 24 kDa) forms. LMW FGF-2 is primarily cytoplasmic and functions in an autocrine manner, whereas HMW FGF-2s are nuclear and exert...

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Publicado no:Mol Biol Cell
Principais autores: Arese, Marco, Chen, Yan, Florkiewicz, Robert Z., Gualandris, Anna, Shen, Bin, Rifkin, Daniel B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Cell Biology 1999
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Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC25296/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10233154/
https://ncbi.nlm.nih.govhttps://doi.org/10.1091/mbc.10.5.1429
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