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Congruence of in vivo and in vitro insertion patterns in hot E. coli gene targets of transposable element Mu: Opposing roles of MuB in target capture and integration

Phage Mu transposes promiscuously, employing MuB protein for target capture. MuB forms stable filaments on A/T-rich DNA, and a correlation between preferred MuB binding and Mu integration has been observed. We have investigated the relationship between MuB-binding and Mu insertion into ‘hot’ and ‘co...

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Main Authors: Ge, Jun, Harshey, Rasika M.
Formato: Artigo
Idioma:Inglês
Publicado: 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529481/
https://ncbi.nlm.nih.gov/pubmed/18556020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.05.032
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