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Screening and Replication using the Same Data Set: Testing Strategies for Family-Based Studies in which All Probands Are Affected
For genome-wide association studies in family-based designs, we propose a powerful two-stage testing strategy that can be applied in situations in which parent-offspring trio data are available and all offspring are affected with the trait or disease under study. In the first step of the testing str...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2529406/ https://ncbi.nlm.nih.gov/pubmed/18802462 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1000197 |
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