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The Atg8 and Atg12 ubiquitin-like conjugation systems in macroautophagy. ‘Protein Modifications: Beyond the Usual Suspects' Review Series

As a lysosomal/vacuolar degradative pathway that is conserved in eukaryotic organisms, autophagy mediates the turnover of long-lived proteins and excess or aberrant organelles. The main characteristic of autophagy is the formation of a double-membrane vesicle, the autophagosome, which envelops part...

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Detalhes bibliográficos
Main Authors: Geng, Jiefei, Klionsky, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529362/
https://ncbi.nlm.nih.gov/pubmed/18704115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/embor.2008.163
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