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Dark Aberrant Crypt Foci with activated Wnt pathway are related to tumorigenesis in the colon of AOM-treated rat

BACKGROUND: To evaluate the relationship between Aberrant Crypt Foci (ACF) and tumorigenesis, we observed the sequential development from ACF to tumor in the colon of azoxymethane-exposed wistar rats. METHODS: Sixty wistar rats were sacrificed at different time points after exposure to azoxymethane...

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Detalhes bibliográficos
Main Authors: Lu, Qing, Jiang, Bo, Lin, Chen, Shan, Tao
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2529269/
https://ncbi.nlm.nih.gov/pubmed/18681964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-27-26
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