N-glycosylation is required for Na(+)-dependent vitamin C transporter functionality

The human sodium-dependent vitamin C transporters (hSVCT1 and hSVCT2) mediate cellular uptake of ascorbic acid. Both these transporters contain potential sites for N-glycosylation in their extracellular domains (Asn-138, Asn-144 [hSVCT1]; Asn-188, Asn-196 [hSVCT2]), however the role of N-glycosylati...

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Hlavní autoři: Subramanian, Veedamali S., Marchant, Jonathan S., Reidling, Jack C., Said, Hamid M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528843/
https://ncbi.nlm.nih.gov/pubmed/18619416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2008.06.120
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