Inactivation of clathrin heavy chain inhibits synaptic recycling but allows bulk membrane uptake

Synaptic vesicle reformation depends on clathrin, an abundant protein that polymerizes around newly forming vesicles. However, how clathrin is involved in synaptic recycling in vivo remains unresolved. We test clathrin function during synaptic endocytosis using clathrin heavy chain (chc) mutants com...

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Bibliographic Details
Main Authors: Kasprowicz, Jaroslaw, Kuenen, Sabine, Miskiewicz, Katarzyna, Habets, Ron L.P., Smitz, Liesbet, Verstreken, Patrik
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2008
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528586/
https://ncbi.nlm.nih.gov/pubmed/18762582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200804162
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