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Inactivation of clathrin heavy chain inhibits synaptic recycling but allows bulk membrane uptake

Synaptic vesicle reformation depends on clathrin, an abundant protein that polymerizes around newly forming vesicles. However, how clathrin is involved in synaptic recycling in vivo remains unresolved. We test clathrin function during synaptic endocytosis using clathrin heavy chain (chc) mutants com...

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Detalhes bibliográficos
Main Authors: Kasprowicz, Jaroslaw, Kuenen, Sabine, Miskiewicz, Katarzyna, Habets, Ron L.P., Smitz, Liesbet, Verstreken, Patrik
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528586/
https://ncbi.nlm.nih.gov/pubmed/18762582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200804162
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