ERK regulates Golgi and centrosome orientation towards the leading edge through GRASP65

Directed cell migration requires the orientation of the Golgi and centrosome toward the leading edge. We show that stimulation of interphase cells with the mitogens epidermal growth factor or lysophosphatidic acid activates the extracellular signal–regulated kinase (ERK), which phosphorylates the Go...

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Detalhes bibliográficos
Main Authors: Bisel, Blaine, Wang, Yanzhuang, Wei, Jen-Hsuan, Xiang, Yi, Tang, Danming, Miron-Mendoza, Miguel, Yoshimura, Shin-ichiro, Nakamura, Nobuhiro, Seemann, Joachim
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2008
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528584/
https://ncbi.nlm.nih.gov/pubmed/18762583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200805045
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