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Synthesis and Characterization of Bioactive Tamoxifen-conjugated Polymers

Macromolecular conjugates of tamoxifen could perhaps be used to circumvent some of the limitations of the extensively used breast cancer drug. To test the feasibility of these conjugates, a 4-hydroxytamoxifen analog was conjugated to a diaminoalkyl linker and then conjugated to activated esters of a...

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Hlavní autoři: Rickert, Emily L., Trebley, Joseph P., Peterson, Anton C., Morrell, Melinda M., Weatherman, Ross V.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528197/
https://ncbi.nlm.nih.gov/pubmed/17929966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bm070413t
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