The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer

The fragile X mental retardation protein (FMRP) is a RNA-binding protein proposed to post-transcriptionally regulate the expression of genes important for neuronal development and synaptic plasticity. We previously demonstrated that FMRP binds to its own FMR1 mRNA via a guanine-quartet (G-quartet) R...

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Autores principales: Didiot, Marie-Cécile, Tian, Zhaoxia, Schaeffer, Céline, Subramanian, Murugan, Mandel, Jean-Louis, Moine, Hervé
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2008
Materias:
RNA
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528169/
https://ncbi.nlm.nih.gov/pubmed/18653529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn472
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