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Engineered Holliday Junctions as Single-Molecule Reporters for Protein-DNA Interactions with Application to a MerR-family Regulator

Protein-DNA interactions are essential for gene maintenance, replication and expression. Characterizing how proteins interact with and change the structure of DNA is crucial in elucidating the mechanisms of protein function. Here we present a novel and generalizable method of using engineered DNA Ho...

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Detalhes bibliográficos
Main Authors: Sarkar, Susanta K., Andoy, Nesha May, Benítez, Jaime J., Chen, Peng R., Kong, Jason S., He, Chuan, Chen, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2528078/
https://ncbi.nlm.nih.gov/pubmed/17880214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja072485y
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