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Identification of Chromatin Remodeling Genes Arid4a and Arid4b as Leukemia Suppressor Genes
BACKGROUND: Leukemia evolves through a multistep process from premalignancy to malignancy. Epigenetic alterations, including histone modifications, have been proposed to play an important role in tumorigenesis. The involvement of two chromatin remodeling genes, retinoblastoma-binding protein 1 (Rbbp...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2528019/ https://ncbi.nlm.nih.gov/pubmed/18728284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djn253 |
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