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TRPV4 channel participates in receptor-operated calcium entry and ciliary beat frequency regulation in mouse airway epithelial cells

The rate of mucociliary clearance in the airways is a function of ciliary beat frequency (CBF), and this, in turn, is increased by increases in intracellular calcium. The TRPV4 cation channel mediates Ca(2+) influx in response to mechanical and osmotic stimuli in ciliated epithelia. With the use of...

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Detalhes bibliográficos
Main Authors: Lorenzo, Ivan M., Liedtke, Wolfgang, Sanderson, Michael J., Valverde, Miguel A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527959/
https://ncbi.nlm.nih.gov/pubmed/18719094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0803970105
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