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Dissecting the roles of MuB in Mu transposition: ATP regulation of DNA binding is not essential for target delivery

Collaboration between MuA transposase and its activator protein, MuB, is essential for properly regulated transposition. MuB activates MuA catalytic activity, selects target DNA, and stimulates transposition into the selected target site. Selection of appropriate target DNA requires ATP hydrolysis b...

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Main Authors: Schweidenback, Caterina T. H., Baker, Tania A.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527872/
https://ncbi.nlm.nih.gov/pubmed/18719126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0805868105
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