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On the fitting of binding data when receptor dimerization is suspected
Mechanistic and empirical modelling are compared in context of dimeric receptors. In particular, the supposed advantages of the two-state dimer model for fitting of binding data with respect to classical approaches such as the two-independent sites model are investigated. The two models are revisite...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527846/ https://ncbi.nlm.nih.gov/pubmed/18536745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.234 |
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