Anti-inflammatory actions of aprotinin provide dose-dependent cardioprotection from reperfusion injury

BACKGROUND AND PURPOSE: Myocardial injury following ischaemia and reperfusion has been attributed to activation and transmigration of polymorphonuclear leukocytes (PMNs) with release of mediators including oxygen-derived radicals and proteases causing damage. EXPERIMENTAL APPROACH: We studied the se...

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Detalhes bibliográficos
Main Authors: Carter, J M, Buerke, U, Rössner, E, Russ, M, Schubert, S, Schmidt, H, Ebelt, H, Pruefer, D, Schlitt, A, Werdan, K, Buerke, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527842/
https://ncbi.nlm.nih.gov/pubmed/18536753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.223
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