Alternating irinotecan with oxaliplatin combined with UFT plus leucovorin (SCOUT) in metastatic colorectal cancer

Tegafur–uracil (UFT) plus leucovorin® (LV, folinic acid) with alternating irinotecan and oxaliplatin were effective and well tolerated in patients with metastatic colorectal cancer (mCRC) in a phase I study. This study expanded the maximum tolerated dose group. Patients aged ⩾18 years had histologic...

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Bibliographic Details
Main Authors: Sheikh, H Y, Valle, J W, Waddell, T, Palmer, K, Wilson, G, Sjursen, A, Craven, O, Swindell, R, Saunders, M P
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2008
Subjects:
Clinical Study
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527827/
https://ncbi.nlm.nih.gov/pubmed/18682717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604499
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