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Lesion Recognition and Cleavage by Endonuclease V: A Single-Molecule Study

Endonuclease V (endo V) recognizes and cleaves deoxyinosine in deaminated DNA. These enzymatic activities are precursors of DNA repair and are fueled by metal ions such as Ca(2+) and Mg(2+), with the former being associated with protein binding and the latter with DNA cleavage. Using the technique o...

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Detalhes bibliográficos
Main Authors: Lin, Jun, Gao, Honghai, Schallhorn, Kathryn A., Harris, Rebecca M., Cao, Weiguo, Ke, Pu Chun
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527690/
https://ncbi.nlm.nih.gov/pubmed/17521169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi6024534
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