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Lesion Recognition and Cleavage by Endonuclease V: A Single-Molecule Study
Endonuclease V (endo V) recognizes and cleaves deoxyinosine in deaminated DNA. These enzymatic activities are precursors of DNA repair and are fueled by metal ions such as Ca(2+) and Mg(2+), with the former being associated with protein binding and the latter with DNA cleavage. Using the technique o...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2527690/ https://ncbi.nlm.nih.gov/pubmed/17521169 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi6024534 |
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