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NO-donating aspirin inhibits angiogenesis by suppressing VEGF expression in HT-29 human colon cancer mouse xenografts

The inhibitory effect of NO-donating aspirin (NO-ASA) on colon cancer has been demonstrated in vivo and in vitro but its mechanism is still obscure. We investigated the effect of NO-ASA on angiogenesis. Four groups of athymic mice (N = 12) bearing subcutaneous xenotransplants of HT-29 human colon ca...

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Detalhes bibliográficos
Main Authors: Ouyang, Nengtai, Williams, Jennie L., Rigas, Basil
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527643/
https://ncbi.nlm.nih.gov/pubmed/18544566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgn127
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