Influence of Cellular ERα/ERβ Ratio on the ERα-Agonist Induced Proliferation of Human T47D Breast Cancer Cells

Breast cancer cells show overexpression of estrogen receptor (ER) α relative to ERβ compared to normal breast tissues. This observation has lead to the hypothesis that ERβ may modulate the proliferative effect of ERα. This study investigated how variable cellular expression ratios of the ERα and ERβ...

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Main Authors: Covaleda, Ana M. Sotoca, van den Berg, Hans, Vervoort, Jacques, van der Saag, Paul, Ström, Anders, Gustafsson, Jan-Åke, Rietjens, Ivonne, Murk, Albertinka J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2008
Teme:
Endocrine Toxicology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527638/
https://ncbi.nlm.nih.gov/pubmed/18644836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn141
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