Influence of Cellular ERα/ERβ Ratio on the ERα-Agonist Induced Proliferation of Human T47D Breast Cancer Cells

Breast cancer cells show overexpression of estrogen receptor (ER) α relative to ERβ compared to normal breast tissues. This observation has lead to the hypothesis that ERβ may modulate the proliferative effect of ERα. This study investigated how variable cellular expression ratios of the ERα and ERβ...

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Détails bibliographiques
Auteurs principaux: Covaleda, Ana M. Sotoca, van den Berg, Hans, Vervoort, Jacques, van der Saag, Paul, Ström, Anders, Gustafsson, Jan-Åke, Rietjens, Ivonne, Murk, Albertinka J.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2008
Sujets:
Endocrine Toxicology
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527638/
https://ncbi.nlm.nih.gov/pubmed/18644836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfn141
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